Scientific Vision Applications
At CTI, we have multiple developers with
science PhDs developing advanced imaging systems and custom
image analysis software. Our clients include numerous
universities, foundations, medical device & pharmaceutical
companies, and others, and our work has led to publication in
scientific journals. For more details, see the example
applications below. See also our
Area Scanning Imaging System (ASIS) on our products page.
-
Adaptive Optics Microscope -CTI developed all the custom LabVIEW
software for controlling a unique microscope which employs adaptive optics to enable orders of magnitude reduction in blurring
in deep biological samples. The research behind this microscope was featured in
Nature Methods, with CTI developer, Daniel Milkie, Ph.D.
as one of the authors.
Nature Methods Article Abstract
-
Crystal Finder - performs automated
high speed imaging and discovery of crystals formed in hanging
drops placed in Well Plates as part of the drug discovery
process.
- Particle Counting System
- counts small drug-filled particles of various
sizes suspended in a fluid enclosed in transparent drug vials.
Offers many advanced features including:
- Automatic "Region of Interest" detection
- Particle size rejection filters
- CellSpotter™
Cell Detection System -
collects, analyzes, and archives microscope images of specially prepared blood
samples, which are then used to detect circulating caner cells.
- CellTracks™ Data Acquisition
- second generation
high-speed image acquisition system for acquiring images of
circulating cancer cells.
- Bio-sample Biaxial Load Tester -
investigates the mechanical properties of
biological and synthetic tissues by stretching samples using a
set of four in-plane stepper motors. In this system, load cells
monitor the forces applied to the sample, while an overhead
camera tracks marker dots on the sample.
- Birefringence Imager - system for acquiring
and analyzing images of birefringent materials in 96 position
well plates. The system automatically controls and XY
table, high resolution camera, light source, and dual polarizing
wheels.
- Confocal Microscope - CTI, along with
researchers at the University of Pennsylvania developed a confocal
microscope with two photon fluorescence capability.
- Tablet Hole Inspection - Size and location
of multiple hole patterns drilled into both sides of
medicine tablets are inspected at a high speed on a conveyor belt.
- Color Tablet Tracking - software allows for the tracking
of the velocity and exposed area of colored tablets
dispersed among white tablets to monitor the mixing process
of tablets.
- Thin Film Defect Detection identifies and quantifies defects in thin films. The system utilizes a high-resolution camera, zoom lens, and XYZ motion control, which allows for imaging over an extended area and for auto-focus control.
CellTracks and CellSpotter are registered trademarks of Immunicon Corp.
